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Project: Surveillance of antibiotic resistance in the Baltic region

TFBS.2002.C
01/11/2002 - 31/12/2004 (26 months)

Project goals

Antibiotic resistance in clinically important bacteria is an emerging and worldwide problem. It severely affects the usefulness of antibiotics in treatment of bacterial infections. One important step in the control of this problem is to apply standardized methodologies and interpretation criteria and to introduce regular surveillance programs of antibiotic resistant bacteria. Surveillance programs based on routine susceptibility data should involve clinical bacteriology laboratories serving defined areas of the country. To initiate a surveillance program the following parts should be attended to: (i) collecting relevant clinical isolates for susceptibility testing, (ii) registering quantitative data, (iii) analysing computerized data, and (iv) modifying and improving methodology and interpretative criteria, if necessary. Regular external quality assurance of methods should be implemented. As a complement to the surveillance system it is necessary to introduce modern DNA-based methods for detection of resistance. These methods could be introduced during an applied training program and need funding in terms of equipment. At the national level, these advanced methods should preferably be centralized to a reference/referral laboratory.

Target Group: Primary target group is the participating laboratories, secondary patients in hospitals and communities in the Baltic Sea States

Output Indicators:

  • International acknowledged standardized methodology should be used for identification and suscept…
    Output: Quality assured data on antimicrobial resistance should be available and reported
    Means of Verification: Standard Operational Procedures (SOPs) should be available for evaluation
    Criteria for Success: SOPs implemented
  • Participation in a external quality assurance programme
    Output: Quality assured data on antimicrobial resistance should be available and reported
    Means of Verification: Data on identification as well as susceptibility testing from the quality assurence programme should be published in a report and available for external assesment
    Criteria for Success: Satisfactory report within two years
    Comments: In 2003 Estonia and Lithuania took part in the quality assurance programme of antibiotic resistance organised by the European network for surveillance of antibiotic resistance, EARSS. In 2004 Latvia will also be included in this programme.
Purpose Indicators:
  • Establisment of national and local networks for coordinating the strategy for containment of anti...
    Purpose: To reduce the transmission of resistant microorganisms and to increase the prudent use of antimicrobials

    Means of Verification: National as well as more local meetings for responsable parties using human resourses from twinning institutions and MOH

    Success Criteria: Establishment of a national committee and networks for coordinating the strategy to contain antimicrobial resistance and improve the prudent use of antimicrobials

    Important Assumptions:

    Comments: In collaboration with project AB24 and by means of a steering committee with representatives from Estonia, Latvia, Lithuania, Russia and Sweden, a joint seminar has been planned for March 2004 in Riga, Latvia. It will focus on antibiotic resistance and infection control. The outcome will be an educational package on recent knowledge in this area.
  • Standard methodology for susceptibility testing and quality assurance (QA) established
    Purpose: To reduce the transmission of resistant microorganisms and to increase the prudent use of antimicrobials

    Means of Verification: Adherence to national or international QA programmes

    Success Criteria: Participating labs enroled in QA programmes using standerdized methods

    Comments: During the seminar which will be held in March 2004 in Riga, standard methodology for susceptibility testing, detection of antibiotic resistance, and quality assurance will be agreed upon.

Results

Antibiotic resistance in clinically important bacteria is an emerging and worldwide problem. It severely affects the usefulness of antibiotics in treatment of bacterial infections. One important step in the control of this problem is to apply standardized methodologies and interpretation criteria and to introduce regular surveillance programs of antibiotic resistant bacteria. Surveillance programs based on routine susceptibility data should involve clinical bacteriology laboratories serving defined areas of the country. To initiate a surveillance program the following parts should be attended to: (i) collecting relevant clinical isolates for susceptibility testing, (ii) registering quantitative data, (iii) analysing computerized data, and (iv) modifying and improving methodology and interpretative criteria, if necessary. Regular external quality assurance of methods should be implemented. As a complement to the surveillance system it is necessary to introduce modern DNA-based methods for detection of resistance. These methods could be introduced during an applied training program and need funding in terms of equipment. At the national level, these advanced methods should preferably be centralized to a reference/referral laboratory.

Target Group: Primary target group is the participating laboratories, secondary patients in hospitals and communities in the Baltic Sea States

Output Indicators:

  • International acknowledged standardized methodology should be used for identification and suscept…
    Output: Quality assured data on antimicrobial resistance should be available and reported
    Means of Verification: Standard Operational Procedures (SOPs) should be available for evaluation
    Criteria for Success: SOPs implemented
  • Participation in a external quality assurance programme
    Output: Quality assured data on antimicrobial resistance should be available and reported
    Means of Verification: Data on identification as well as susceptibility testing from the quality assurence programme should be published in a report and available for external assesment
    Criteria for Success: Satisfactory report within two years
    Comments: In 2003 Estonia and Lithuania took part in the quality assurance programme of antibiotic resistance organised by the European network for surveillance of antibiotic resistance, EARSS. In 2004 Latvia will also be included in this programme.
Purpose Indicators:
  • Establisment of national and local networks for coordinating the strategy for containment of anti...
    Purpose: To reduce the transmission of resistant microorganisms and to increase the prudent use of antimicrobials

    Means of Verification: National as well as more local meetings for responsable parties using human resourses from twinning institutions and MOH

    Success Criteria: Establishment of a national committee and networks for coordinating the strategy to contain antimicrobial resistance and improve the prudent use of antimicrobials

    Important Assumptions:

    Comments: In collaboration with project AB24 and by means of a steering committee with representatives from Estonia, Latvia, Lithuania, Russia and Sweden, a joint seminar has been planned for March 2004 in Riga, Latvia. It will focus on antibiotic resistance and infection control. The outcome will be an educational package on recent knowledge in this area.
  • Standard methodology for susceptibility testing and quality assurance (QA) established
    Purpose: To reduce the transmission of resistant microorganisms and to increase the prudent use of antimicrobials

    Means of Verification: Adherence to national or international QA programmes

    Success Criteria: Participating labs enroled in QA programmes using standerdized methods

    Comments: During the seminar which will be held in March 2004 in Riga, standard methodology for susceptibility testing, detection of antibiotic resistance, and quality assurance will be agreed upon.

Location

  • Arkhangelsk oblast
  • Kaliningrad oblast
  • Murmansk oblast
  • Republic of Karelia
  • Saint-Petersburg
  • Related Organisations

    Counterparts:   no information
    Beneficiaries:   no information
    Financiers:   Task Force on Communicable Disease in the Baltic Sea Region (TFBS)
    Contractors:   no information

    Project Budget

    111 000 Euro.

    Personnel

    The following table contains the persons involved in the project and the organisations they belong to. In order to get contact details about a person or an organisation, please click on its name.

     
    Position in project
    Name of
    the Expert
     
    Current work place
    Place of
    Performance
    Programme Group Member Olsson-Liljequist B., MD Chief Microbiologist

    Additional information

    Preconditions: Quality assured laboratories, will to national and international collaboration, adherence to internationally approved protocols, e.g. NCCLS, regular reporting in a electronic format compatible to WHONET.

    Topics: 

    This project is characterised by the topics below. Please click on one of these topics to see a list of other projects with that topic.

    Disease Prevention

    Epidemiology and statistics

    ФГУ «ЦНИИОИЗ Минздравсоцразвития РФ» официальный сайт

     Copyright  2002—2021, Federal Public Health Institute
     The project is funded by WHO/CIDA Health Care Policy and Stewardship Programme in Russia
     Developed in co-operation with the EU funded Tacis "North West Health Replication Project"
    WHO EU